The second of three derbies in the space of just four weeks kicks off in the Camp Nou at 9.30pm CET.
The game will be preceded by a special farewell ceremony for Javier Mascherano, whose departure from the club was announced this week.
The Barça squad was announced on Wednesday evening, the main news being the inclusion for the first time of the two winter signings, Philippe Coutinho and Yerry Mina.
There's further good news in the returns of both Andrés Iniesta and Paco Alcácer from injury.
There are question marks over the fitness of Espanyol’s Pablo Piatti, José Manuel Jurado and Javi Fuego, but in order to avoid giving away any clues, they won’t be announcing their squad until the day of the game.
Ernesto Valverde gave his pre-match press conference on Wednesday. So did Espanyol boss Quique Sánchez Flores, who commented that “a 1-0 lead doesn’t give us any room for speculation … Their game with Celta is a good example of what we can expect. Barça will be intense from the start and will try to control the game, but we know that every goal we score tomorrow counts double.”
“We don’t think it’s impossible … And we won’t do anything special with Messi. Teams in the Champions League have managed to cut him out of both legs, but you do that by closing down spaces, limiting his field of action.”
The defeat in the first leg was Barça’s first loss in 29 games, but they bounced back with a tremendous 5-0 win at Betis to move 11 points clear at the top of the Liga table.
Espanyol, meanwhile, have been having an erratic year. But after failing to win on the road all season, their two away trips in January have both been victorious, 1-0 at Malaga in the league and 2-0 at Levante in the cup.
This is the nineteenth time that the two local rivals have met in the Spanish Cup. In the early years, it was Espanyol who had the slight upper hand, but their 5-3 aggregate victory in 1960/61 was the last time they progressed at Barça’s expense.
Since then, Barça have won all nine cup clashes, In fact, last week was only the second time in that period that they have even lost a leg. Back in 1969/70, Espanyol won 2-1 at their old Sarrià stadium, but the blaugrana turned things around with a 3-1 triumph at the Camp Nou. Let’s hope that scenario gets repeated in 2018!
Иниеста и Пацето са в групата
Коу и Мина може да направат дебюти